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Sex distribution and mean age are also listed for each brain region based on diagnosis group (as the number of participants collected varied for each brain region

Whilst additional studies are needed to understand the mechanistic basis for these differences, the researchers suggest that some of the patterns observed can be partially explained by the fact that sex hormones such as oestrogen can regulate antioxidant enzyme levels and activation of T cells

Biomarkers are important in confirming AD pathology and guiding targeted therapies 6

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