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Debunking the myth: Safety profile: GLP-1 agonists have undergone extensive clinical testing to ensure their safety

Koehler (47) reported that GLP-1RAs may induce apoptosis by altering cell morphology in vitro , possibly by activating cAMP expression and inhibiting the activities of the signaling kinases glycogen synthase kinase 3 and ERK1/2, thereby inducing apoptosis and inhibiting the growth and survival of colon cancer cells

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By modulating various metabolic pathways, MOTS-c influences processes such as glucose metabolism, insulin sensitivity, and fat oxidation