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Description

As a result of the numerous benefits that have been discovered, 7nAChR is regarded as a potentially beneficial therapeutic target in CNS disorders, including neurodegenerative diseases like Alzheimers disease (AD) and Parkinsons disease, psychiatric disorders like autism and schizophrenia, and cerebrovascular diseases like ischemic stroke, and hemorrhage stroke [29,30,31,32]

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It underscores the misapplication of effect sizes, a lack of sensitivity analyses, and the absence of subgroup estimations as cumulative factors invalidating the real-world clinical reliability of Pradelle et al.'s findings

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