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The most significant clinical evidence for retatrutide to date comes from a Phase 2 trial published in the New England Journal of Medicine in 2023 (Jastreboff et al., NEJM 2023)

It can also boost immunity and support overall cellular health by neutralizing free radicals

For those with specific health concerns or those who are pregnant or breastfeeding, it is important to speak with a healthcare professional before starting any new supplement

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A year later, the brand went fully mainstream by hitting Target shelves across the US, followed by a January 2026 launch in Walmart stores nationwide