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7).Nuclear factor (erythroid-derived 2)-like 2 factor is the master regulator of antioxidant protein expression in the cell which protects it from oxidative damage triggered by injury and inflammation, whereas inducible nitric oxide synthase (iNOS) is responsible for producing large quantities of NO

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The enzymes which carry out the process of reduction also require a co-enzyme NADPH (nicotinamide adenine dinucleotide phosphate hydrogenase) [6]

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