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An additional study with 100 and 200 M doses of APR-246 showed a dose-dependent decrease in G1 that is both p53 and P72R-independent (Supplementary Fig

Research on rat models with induced arthritis documents reduced cartilage degradation and improved limb function scores in BPC-157-treated subjects

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Variants such as rAAV-PHP.B and a second generation rAAV-PHP.eB contain an engineered capsidcontributing to an unprecedented efficiency in crossing the BBB upon intravenous injection, along with high diffusion capacity into both neurons and glia of mice [163,164,165,166]