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Ozempic (semaglutide), originally a diabetes medication, is now widely prescribed for weight loss

During the last 5 h of treatment (1924 h), cells were exposed to 3,3-dioctadecylindocarbocyanine-labeled low-density lipoprotein (Dil-LDL, 10 g/mL), then washed twice with pre-warmed (37C) HBSS containing 20 mM HEPES before analysis

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These changes improve calculated cardiovascular risk scores and may reduce requirements for lipid-lowering medications over time

The GLP-1 market has been periodically hampered by shortages, and Lilly is betting that putting the drug into this new form will allow them to produce a more robust supply