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In pancreatic beta cells, this process is glucose-dependent , meaning that insulin secretion is enhanced only when blood glucose levels are elevateda critical safety feature that reduces the risk of hypoglycaemia compared to other antidiabetic agents such as sulphonylureas

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Nearly half of the people taking CONTRAVE along with diet and exercise lost 5% or more weight and kept it off vs 23% of people on diet and exercise alone

Numerous research papers support its fat-dissolving abilities, and its widely used in dietary supplements for weight loss