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As GCs continued to be implemented over decades of use, closer inspection brought to light further complexities including steroid resistance leading to in vivo and in vitro analyses to better understand these mechanisms and the pathways involved in the hopes for targeted therapies to both overcome this resistance and enhance GC efficacy

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CRC, Taylor and Francis, Boca Raton, pp 683732 Sciuto AM (1997) Antioxidant properties of glutathione and its role in tissue protection

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