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Description

Sitagliptin works by inhibiting the DPP-4 enzyme, which normally breaks down incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)

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When this is oxidized and cleaved, the products are acetyl-CoA and propionyl CoA

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Summary: GLP-1 receptor agonists do not directly increase fertility, but may indirectly improve reproductive function through weight loss and metabolic improvements in people with obesity-related fertility impairment

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Research shows that people with elevated inflammatory markers respond poorly to standard antidepressants

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