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This is especially crucial for patients with neurological symptoms, which can easily become permanent if under-treated long enough

10.1016/s0197-4580(03)00041-1 [DOI] [PubMed] [Google Scholar] Stavric B (1988) Methylxanthines: toxicity to humans

This blend is a laboratory research material used to examine how two peptides may interact with cellular signaling systems and structural pathway responses in controlled experimental models

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But acute 5-hour measurement and chronic long-term exposure are different things