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Moreover, cGAS-driven micronucleophagy also dampens cGAMP production and altogether exerts a negative effect on cGAS-STING signaling and innate immunity (155)

10.1038/s41573-024-00979-4 16 GreilR.Greil-ResslerS.WeissL.SchnliebC.MagnesT.RadlB.et al (2018)

Studies like NeoPAL and CORALLEEN suggest that aromatase inhibitors combined with CDK4/6 inhibitors provide similar long-term survival benefits compared to neoadjuvant chemotherapy but with slightly improved breast conservation rates and fewer chemotherapy-related adverse effects

An anti-inflammatory agent that reduces the production of inflammatory molecules called cytokines

To illustrate this point further, consider broccoli, known for its high glutathione content