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Similar to RNK06138, RNK06395 showed specific accumulation and prolonged pharmacokinetics in tumors compared to those in normal tissues in the MOLP-8 xenograft model, as well as higher drug concentrations in tumors than in tissues 7 days after administration (Fig

Marble burying testing showed no significant difference in the percentage of marbles buried at baseline (70 12) and post-MT-II (65 11)

In HepG2 cells, protein expression of NQO1 was either significantly decreased or remained unchanged upon treatment with oleic acid, a combination of fatty acids or fructose (Jin et al

L-carnitine reduces inflammatory response via the transfer of -oxidized long-chain fatty acids in mitochondria and the excretion of toxic substances in fatty acid metabolism (69)

A concentration reported in one paper should be treated as a starting point, not as a universal protocol