glutathione herxheimer with Cofactors Chemical structure of glutathione at

Glutathione (GSH): Glutathione provides major intracellular antioxidant activity, GSH is essential for neutralizing free radicals, regenerating vitamins C and E, supporting mitochondrial energy metabolism, and protecting DNA from oxidative stress

Yang M, Darwish T, Larraufie P, Rimmington D, Cimino I, Goldspink DA, Jenkins B, Koulman A, Brighton CA, Ma M, Lam BYH, Coll AP, ORahilly S, Reimann F, Gribble FM (2021) Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells

Glutathione helps by maintaining the skins overall health, allowing Vitamin C to do its job more effectively

Older skin cells cannot be shed fast enough, so they pile up on the surface as thick, silvery, flaky areas of dead skin

Schopler, E., Reichler, R