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Editorial Advisory Board Member, Harvard Health Publishing Teresa Fung, ScD, RD Contributor

For studies requiring sustained peptide exposure, twice-daily dosing maintains more consistent plasma levels than single daily administration

Nrf2 depletion in macrophages leads to increased foam cell formation, increases the M1 inflammatory phenotype with enhanced expression of pro-inflammatory monocyte chemoattractant protein-1 and interleukin-6, and aggravates atherosclerosis (244, 245)

Many patients achieve optimal results through medication alone, without additional interventions that could trigger side effects