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NAC is a promising augmentation option for at least a subset of patients due to its generic availability, affordability and favourable tolerability profile

Interestingly, differences in prooxidative parameters were more profound in acute coronary syndrome patients compared with coronary artery disease patients indicating that the acute form of coronary artery disease is more susceptible to oxidative damage, suggesting that use of antioxidant therapy may be warranted to reduce oxidative stress in this disorder (154)

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They have also identified a plethora of pathological molecular and neuronal phenotypes observed in schizophrenia patients, confirming the translational significance of these pre-clinical models [6, 7]