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Summary of Evidence Data from two RCTs [27, 28] and 6 observational studies [29-34] from the systematic review reported outcomes which were deemed critical or important to clinical decision making for this question and were used to inform the panels decision

Osteoporosis occurs when this balance shifts in favor of resorption, meaning bone is being broken down faster than it is being rebuilt, and bone mineral density progressively declines (Fger-Samwald et al., 2020)

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Be patient and persistent