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The JPML agreed with arguments that the NAION cases share common defendants, counsel, and overlapping scientific issues with the gastrointestinal injury litigation already pending before Judge Marston

Buthionine sulfoximine (BSO) can selectively inhibit r-glutamylcysteine synthase (R-GCS), thus preventing the synthesis of dipeptides from glutamic acid and cysteine

Preparation of D-psicose from D-fructose by immobilized D-tagatose 3-epimerase

Regular monitoring of renal function, HbA1c, and body weight is recommended, with treatment adjustments made according to clinical response and tolerability

Outcomes included lean body mass (DXA), upper and lower body strength, 6-min walk distance, quality of life, and mTOR protein expression