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Most of these proteins act as chemotactic factors at the site of inflammation, promoting the initial recruitment of satellite cells, neutrophils, monocytes, and, later, lymphocytes for tissue repair [52, 62,63,64,65]

7.1.4 Response to treatment should be assessed after exclusion of sub-optimal dosing, non-adherence, alternative etiologies, co-morbidities, and autoimmune sclerosing cholangitis/overlap syndrome (LOE 5, Strong recommendation)

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We then separated patients into 3 groups based on measured levels of estradiol (Fig