It met its primary endpoint, with a statistically significant improvement in pain with Xiaflex versus placebo, as measured by the Average Daily Pain Intensity on the Numeric Rating Scale (NRS), which Keenova said was a "clinically meaningful" result
This work was supported by grants from the Natural Science Foundation of Guangdong Province (2023A1515012187, 2024A1515030281), Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-communicable Diseases (2022B121203003), Discipline Construction Project of Guangdong Medical University (4SG21229G), Zhanjiang City Science and Technology Development Special Funds Competitive Allocation Project (2021A05083), Zhanjiang Science and Technology Project (2019A01027), National Clinical Key Specialty Construction Project (Institute of Nephrology, Affiliated Hospital of Guangdong Medical University), The Affiliated Hospital of Guangdong Medical University funded the research of high-level talents (10403Z20180001)
Table 1 lists the solubility product constants of some ionic compounds
But there are fewer defenses for injectable drugs, and any contamination could cause health problems, he said
Animal models of ALS show abnormal transport of mitochondria in their motor neurons which could further contribute to the progression of the disease (De Vos 2007)
