Anchoring trials include STEP (semaglutide, The New England Journal of Medicine , 2021), SURMOUNT (tirzepatide, NEJM 2022), and SURMOUNT-OSA (tirzepatide for obstructive sleep apnea, NEJM 2024)
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2 mg once weekly represents the most commonly reported starting point in published Phase 2 data, not a universally fixed starting dose
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Pharmacovigilance status of DPP-IV inhibitors With an ideology to work on the crux of the matter, DPP-IV to manage diabetes, orally active small molecules called DPP-IV inhibitors have already been introduced in the market since 2006 (51)
