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The early pathogenesis of diabetic retinopathy and its attenuation by sodium-glucose transporter 2 inhibitors

More specifically, it has been reported that following ischemia, oxidative stress, or acidosis injury in rat caECs, CMs, and aortic SMCs, sAC-dependent apoptosis is triggered by translocation of sAC from the cytosol to mitochondria with submitochondrial PKA activation, Bax phosphorylation, and cytochrome c release (4548)

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Approval is based on whether your medical case meets BCBS exception criteria