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4.1 Signals of adverse events We observed that metabolic and nutritional adverse reactions were more frequently reported by females (Table 1), which has previously been interpreted as a greater inclination for females to report AEs to FAERS ( Exenatide (n = 10,450), dulaglutide (n = 4,847), liraglutide (n = 2,860), semaglutide (n = 2,905), and tirzepatide (n = 1,089) had the greatest number of reported AEs, and the highest number of AEs reported on the effects of appetite, as reflected in our analyses of the HLT stratum (Supplementary Table S2)

Future studies should examine BHB at various time points during the day using a home blood ketone meter

Protein takes longer to digest than simple carbohydrates, but it does not trigger the same level of GI distress as fats

Treatment is limited to a maximum of 2 years

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