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Ovarian microbiota, ovarian cancer and the underestimated role of HPV

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Methods Embase, PubMed, Web of Science, the Cochrane Library, and ClinicalTrials.gov website were searched until 25 May 2025

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Preclinical studies identified several mechanistic pathways through which curcumin may alleviate DACD, including anti-inflammatory and antioxidant effects via NF-B, NLRP3, AKAP150/PKA/PP2B, miR-146a-5p/ERK, BDNF/TrkB, ROS-ERK1/2, GABA receptors, Keap1-Nrf2-ARE, and regulation of intestinal flora