Alcohol-associated PAGln production and cardiovascular dysfunction are transmissible traits To address the relative contribution of alcohol-induced gut microbial reorganization towards increased PAGln levels and subsequent cardiovascular dysfunction, we performed microbial transplantation of gut commensals from PF and AF mice into nave mice using a previously reported protocol with modifications as described (Fig
1 Although recent studies have reported a connection between NAION and the use of Semaglutide, a Glucagon-Like Peptide-1 (GLP-1) receptor agonist approved by the US Food and Drug Administration (FDA) in December 2017 for type 2 diabetes (T2D) and in December 2022 for obesity, further investigation is needed to fully understand the clinical implications of this association
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Singh P, Pandit S, Garnaes J, Tunjic S, Mokkapati VR, Sultan A, et al
Melanotan II is supplied as a lyophilized powder and should be reconstituted with bacteriostatic water (BAC water) before use
