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Semaglutide mitigates steatosis and insulin resistance in high-fat-diet mice. Metabolism Research , 18 (2), 90101

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Side Effects and Precautions Known Risks (Animal Studies + Anecdotal Reports) Potential for over-stimulation of neurogenesis , which is beneficial short-term but may carry unknown long-term risks Some users report: Mild headaches Irritability or emotional blunting Temporary insomnia if taken late in the day Theoretical Risk: Tumor Growth

This central mode of action is why PT-141 can increase the desire for sex (something pure blood-flow drugs cannot do)