Cons: Price: Slightly higher compared to other capsule forms
According to the UK SmPC, these include: Nausea (very common, affecting more than 1 in 10 patients) Diarrhoea and constipation (very common) Vomiting and abdominal pain (common) Decreased appetite and dyspepsia (common) These symptoms are generally mild to moderate in severity and tend to diminish over time as the body adjusts to the medication
This theory is supported by the discovery of adrenal atrophy upon autopsy ( CAI in PWS is not well understood, as studies have reported varying results (ranging from 0% to 60%) using different dynamic tests, such as the insulin tolerance test (ITT), metyrapone test (MT), glucagon test (GT), and the currently most used low-dose and standard dose Synacthen stimulation test (LDSST and SDSST) ( Table 1 ) ( Table 1 Summary of the studies with stimulation tests for central adrenal insufficiency in PWS
Always consult a qualified medical professional before starting any new supplement, especially if you are pregnant, nursing, or managing a chronic condition
These approvals highlight the ongoing efforts to combat chronic diseases and improve patient outcomes