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Multiple studies, usually done during endoscopies (EGDs) with or without colonoscopies, have shown that patients on GLP-1 receptor agonists have residual gastric contents when fasting from solids for 8 hours (70% of patients, n=10) and when fasting from solids for up to 16 hours (13.1% after 10 hr, n=84
N Engl J Med 369: 1317-1326, 2013
About 15% selected a clinical falsehood, while 14% admitted they had no idea
6.3 Clinical Symptoms That Should Prompt Assessment Patients on GLP-1 therapy should seek review if experiencing: Persistent fatigue Hair thinning beyond expected telogen shift Neurological symptoms (numbness, tingling) Muscle weakness Persistent vomiting Severe dietary restriction These symptoms are non-specific but warrant nutritional evaluation
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