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Injectable semaglutide 2.4 mg (Wegovy) produces somewhat greater weight loss than orforglipron: approximately 14.9% at 68 weeks in the STEP 1 trial versus 11.2% at 72 weeks with orforglipron 36 mg in ATTAIN-1

529,530,531,532 This approach may serve as an adjunctive therapy for difficult-to-treat pathogens like Aspergillus fumigatus

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