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Approved by the FDA in 2021 for treating type-2 diabetes, GLP-1s have more recently been used to great effect in combating obesity, a condition that affects some 42% of American adults

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Among the two polyunsaturated acylcarnitines, octadecadienyl carnitine (C18:2) was found to be decreased in the patients compared to the controls without generating a statistically significant difference (P = 0.113), whereas the concentration of tetradecadienoylcarnitine (C14:2) of the patients and the healthy controls did not differ

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However, panellists also agreed that, in the absence of evidence and clear, consistent guidance, there is a need for an expert-endorsed treatment algorithm, to support clinical decision-making for adults with CKD and T2D