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[28] Thimmulappa RK, Mai KH, Srisuma S, et al

Immunity 42 , 11591170 (2015)

GGCT affects the proliferation by disrupting the redox balance in tumor cells To explore the biological function of GGCT, we analyzed transcriptome data by knocking down GGCT in MHCC97H cells (GSE282603) and compared it with the published data from PC3 cells (GSE154584)

Neuroreport 30, 813

The accumulation of intracellular ROS caused by low levels of tert-butyl hydroperoxide can induce the activation of p53 and lead to cell death, which can be specifically inhibited by the ferroptosis inhibitor Fer-1 but cannot be inhibited by other kinds of cell death pathway inhibitors, indicating that the form of death is ferroptosis