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At daily 1 mL, about 4 weeks

At maintenance doses of 2.0mg or 2.4mg, the volume increases significantly

Because a large number of comparisons were performed on the relative abundance data, main effect results from these analyses also underwent a BenjaminiHochberg false discovery rate (FDR) correction for multiple comparisons, and instances where a result was significant after this correction have been duly noted

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Pernicious anemia , an autoimmune disease that destroys intrinsic factor production, prevents adequate B12 absorption regardless of dietary intake or oral supplementation attempts