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The importance of commensal bacteria in the gut has been demonstrated previously, for example, germ-free mice displayed an underdeveloped mucous layer as well as reduced mucin production and IEC proliferation, each of which are required for gut barrier health (Kim and Ho 2010)

Concurrently, patients also experienced sustained weight loss of 2.33.0 kg ( p 0.015 vs

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The metabolic profile is very similar to that in column 3 except that now the intracellular SAH concentration does not decline but instead increases by 24% in line with the clinical data