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The heart disease-related ICD-10 codes used in the model are as follows: C16: Malignant neoplasm of the stomach C34: Malignant neoplasm of bronchus and lung C50: Malignant neoplasm of the breast G20: Parkinsons disease I21: Acute myocardial infarction I48: Atrial fibrillation and flutter I50: Heart failure I63: Cerebral infarction I67: Other cerebrovascular diseases J18: Pneumonia, unspecified organism MACE prediction code-embedded model The second model, the MACE Prediction Code-Embedded Model , aims to predict MACE within one year following PCI or CABG [45]

This pathway activation results in increased endothelial nitric oxide synthase (eNOS) activity, promoting vasodilation and new blood vessel formation

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Changes in thyroid function tests are generally not observed, despite theoretical concerns based on animal studies showing thyroid C-cell effects

The approximate molecular weight is 1,419.5 g/mol