Bach LA
M.ParvathareddyJ.WodowskiA
IGF-1 LR3, DES(1-3) IGF-1, and PEG-MGF: IGF-1 Analogue Cluster IGF-1 LR3, DES(1-3) IGF-1, and PEG-MGF are three synthetic analogues of insulin-like growth factor 1 engineered for distinct half-life, IGFBP binding, and receptor-activation profiles
It combines N-Acetyl-L-Cysteine Ethyl Ester (NACET) with liposomal minerals (magnesium, zinc, selenium) and key cofactors molybdenum and glycine to support efficient cellular function
All these effects could lead to a potential increase in quality-adjusted life years for patients receiving HFR compared to other dialysis techniques, which would be sufficient to justify the additional cost, as has been described with other adsorptive techniques.95 Guidance for future research Despite the potential advantages of HFR over high-flux HD and OL-HDF with high convective transport, this technique could benefit from improvements in the design of currently available prototypes