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Plasma concentrations decline with age - from approximately 200 ng/mL at age 20 to under 80 ng/mL by age 60

That can affect body weight over time, but again, indirectly

After consideration of the public comment we received and our review of the device pass-through application, we have determined that the aprevo Cervical ACDF System does not meet the device category eligibility criterion at 419.66(c)(1) because it is appropriately described by an existing category or a category previously in effect

Commenters stated that the limited claims data (less than 1 year) does not accurately reflect the costs of providing SAINT and that CMS should not use the small dataset that is available for determining the rates for CY 2026

Customers are responsible for determining the correct codes when billing