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Take 1 capsule, up to 3 times daily, about 30 minutes before meals

Im still on my first bottle

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EMBO Rep (2006) 7(9):8805.10.1038/sj.embor.7400779 117 BertolottiAWangXNovoaIJungreisRSchlessingerKChoJHet alIncreased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice