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The mode of action of auranofin hinges on its interaction with the redox-active center of TXNRD, specifically its selenocysteine-containing site, consequently impeding TXNRD function [236]
10.1038/s41401-020-00518-y Acta Pharmacol
Inspired by the unique characteristic of Se-based nanomaterials, the Te with the similar chemical properties to Se was developed for selective cancer therapy by Yang and co-workers ( 6 6- under intracellular overexpressed H 2 O 2 condition and boost enhanced ROS generation in the tumor site
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