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The gut, being the largest mucosal interface between the external environment and internal physiology, is a unique redox-sensitive organ
This polymorphism was retrospectively found to be over-represented in patients developing hepatotoxicity following intentional paracetamol overdose [39]
FGF21 has originally been described as a fasting hormone that is upregulated in the liver via PPAR and partly regulates ketogenesis during starvation or KDs
Additionally, the evidence was too limited to assess the impact on quality of life or mental and physical fatigue
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