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B12 pooling can occur when there is not adequate transport

Results can vary based on individual health, diet, and exercise

A meta-analysis of randomized controlled trials found they can improve tendon structure, strength, and post-exercise recovery when combined with resistance training, though the quality of evidence remains moderate. Innovation is exciting, but recommending injectable, unregulated peptides to patients, without clinical validation should give us pause

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Medical Conditions, Surgeries, and Medications Lack of intrinsic factor (a protein made in the stomach thats needed for B12 absorption) - this condition is called pernicious anemia Thyroid disease HIV/AIDS (human immunodeficiency virus/acquired immunodeficiency syndrome) Autoimmune diseases like type 1 diabetes, where the immune system in the body attacks its own tissues Gastric bypass surgery (weight loss surgery) Chronic gastritis surgery Certain medications like heartburn drugs (proton pump inhibitors) which reduce stomach acid production Who Is At Risk of Vitamin B12 Deficiency