Depending on the medication, people can lose around 13%20% of their body weight with semaglutide (Wegovy, Ozempic, Saxenda) and 15%21% with tirzepatide (Zepbound, Mounjaro), on average
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Essential Supplements for Bone Protection A targeted supplement regimen can make a significant difference in maintaining bone density: Calcium + Vitamin D3 Daily requirement : 1,000-1,200mg calcium and 2,000-5,000 IU vitamin D3 Best forms : Calcium citrate (more easily absorbed than calcium carbonate), vitamin D3 (cholecalciferol) Timing : Split calcium doses throughout the day for better absorption Vitamin K2 Daily requirement : 100- 200 mcg Function : Directs calcium to your bones rather than soft tissues and blood vessels Forms : MK-7 form has better bioavailability than MK-4 Magnesium Daily requirement : 320-420mg daily Forms : Magnesium glycinate or malate for better absorption and less digestive discomfort Benefits : Works synergistically with calcium and vitamin D Collagen Peptides Daily requirement : 10-15g Function : Provides the protein matrix upon which bone mineralization occurs Bonus : Also supports skin, hair, and joint health 2
Kidney International Supplements 2016;6(1):20e8
For researchers and patients navigating these medications together, SeekPeptides offers comprehensive protocol guides, dosing calculators , and a community of people who have successfully managed this exact combination
