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MECHANISM CATEGORIES SAFETY Side effects GI: nausea, vomiting (titration-dependent) Injection-site reactions Hypoglycemia risk when combined with insulin Known interactions Insulin additive hypoglycemia risk Contraindications History of MTC or MEN2 (theoretical class effect) REGULATORY STATUS FDA Not yet FDA-approved as of 2026-05

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Beyond treating metabolic issues, these drugs show promise in improving mental health and potentially reducing dementia risk, as indicated by Novo Nordisk's research

Proteins were then ranked by log 2 fold change (coculture over monoculture)