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SURPASS-3: Body Composition Data A DEXA substudy in SURPASS-3 (N=1,444) quantified that tirzepatide reduced fat mass by approximately 33% more than insulin degludec on a matched weight-loss basis [24]

As explained, there is a rationale for the combined use of basal insulin and GLP-1RAs

Through a GLP1 lens, hydration matters because shoppers may be eating less and looking for lowsugar, lowcalorie ways to keep hydration, electrolytes and gentle energy ticking over