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These findings imply that emodin protects hepatocytes from APAP-induced liver damage by activating Nrf2-mediated antioxidant stress pathways, inhibiting the NLRP3 inflammasome, and downregulating the cGAS-STING signaling pathway (Shen et al., 2022)

Trans-4-(aminomethyl)cyclohexane carboxylic acid (T-AMCHA), an anti-fibrinolytic agent, accelerates barrier recovery and prevents the epidermal hyperplasia induced by epidermal injury in hairless mice and humans

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In addition, differences in corresponding changes in expression levels of genes associated with dendritic cell maturation, interferon signaling, and NF-B signaling pathways in circulating T cells and monocytes have been noted (Jangi et al., 2016)