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Similarly, mice exposed to CUMS for 6 weeks showed an increased interferon-gamma (IFN-) and decreased anti-inflammatory IL-10 levels, demonstrating anti-inflammatory suppression with further pro-inflammatory activation (Jia et al., 2024)

A typical dosing schedule involves taking metformin orally with meals (500-1,000 mg morning and evening) and administering the Ozempic injection once weekly at a consistent time

doi: 10.1016/S0140-6736(21)01443-4 37 Del PratoSKahnSEPavoIWeerakkodyGJYangZDoupisJet al

These medications are FDA-approved for chronic weight management in adults with a BMI of 30 or greater (obesity) or a BMI of 27 or greater (overweight) with at least one weight-related health condition such as hypertension, type 2 diabetes, or high cholesterol