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Dark urine while taking semaglutide is often caused by simple dehydration, concentrated urine, or harmless factors like vitamins and foods

Thus, the use of extraphysiologic dopamine levels could produce confounding results by increasing the activation of receptors that may not be physiologically relevant and inducing aberrant effects due to cell death and the subsequent response to factors released from apoptotic cells

Methods Mol Biol 2358:4571

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