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Asian Journal of Psychiatry, 6 (1), 29-34

The pancreatic cells harbour GLUT2 transporters (similar to the small intestine) and these transporters uptake the glucose from the blood (specifically the pancreatic -cells)

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However, a 2022 study in the journal Nutrients found that one of the ingredients in Lemme, Morosil red orange fruit extract, helped participants lose a small amount of weight though notably while also eating a healthy diet and exercising compared to those taking a placebo

This makes retatrutide the first triple-receptor agonist to reach late-stage clinical trials, representing the next step in the evolution of incretin-based metabolic research compounds