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Li B, Pan L, Zhang H, Xie L, Wang X, Shou J, Qi Y, Yan X

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The treatment groups received weekly intra-articular injections of A-CDs (100 mg/mL, 100 L) or AA-CDs (100 mg/mL, 100 L) twice weekly for 8 weeks

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FDX1 serves multiple roles in this process: It catalyzes the lipid acylation of pyruvate dehydrogenase and -ketoglutarate dehydrogenase, and enhances copper ion toxicity by converting Cu2+ to the more toxic Cu+ (184)

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