It appears safe to continue these medications before a procedure requiring anaesthesia or sedation, with minor precautions like abstaining from solid food for a day to minimize any potential risk of aspiration. Recent reports and studies suggest that taking GLP-1 medications is associated with slower digestion with a larger amount of food remaining in the stomach
If we can consider Nrf2 a protective factor when it prevents oxidative stress and inflammation associated with tumourigenesis, we have to consider it an oncogenic factor when it is hyper-stimulated or overexpressed, thus causing the opposite effects
Gastrointestinal symptomsparticularly nausea, vomiting, diarrhoea, and constipationare the most frequently reported adverse effects of GLP-1 receptor agonists, occurring in 2050% of patients depending on the specific agent and dose according to clinical trials and SmPC data
284 MAT2A Methylthioadenosine phosphorylase (MTAP)-deficient tumors account for ~15% of solid tumors, including ~15% of NSCLC, 28% of esophageal cancer, 26% of bladder cancer, and 10% of esophagogastric cancer
Morris MC, Schneider JA, Li H, Tangney CC, Nag S, Bennett DA et al
