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7 Conclusions and outlook Bilirubin has a complex interaction with cancer, and bilirubin can inhibit tumorigenesis and development through a variety of mechanisms, including influencing cellular redox reactions, signaling, and the immune system, while the effects of cancer on bilirubin have derived several prognostic models

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In aged erythrocytes, on the other hand, a high intracellular Ca 2+ level likewise plays a particular role in the initiation of different apoptotic pathways